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Journal of Ayurveda and Integrative Medicine Journal of Ayurveda and Integrative Medicine
 
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LETTER TO THE EDITOR
Year : 2011  |  Volume : 2  |  Issue : 2  |  Page : 51  

Anticataract potential of Triphala


Wiwanitkit House, Bangkhae, Bangkok, 10160, Thailand

Date of Web Publication29-Jun-2011

Correspondence Address:
Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok, 10160
Thailand
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DOI: 10.4103/0975-9476.82513

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How to cite this article:
Wiwanitkit V. Anticataract potential of Triphala. J Ayurveda Integr Med 2011;2:51

How to cite this URL:
Wiwanitkit V. Anticataract potential of Triphala. J Ayurveda Integr Med [serial online] 2011 [cited 2014 Nov 1];2:51. Available from: http://www.jaim.in/text.asp?2011/2/2/51/82513

Sir,

I read the recent publication on the anticataract potential of Triphala (TP) with a great interest. [1] Gupta et al., concluded that "TP prevents or retards experimental selenite-induced cataract. [1]" This finding is interesting. Recently the usefulness of TP been proposed for many diseases including metal caries. [2] However, the disturbance of Cytochrome P450 is an important toxicopharmacological effect of TP that needs to be mentioned. [3] Ponnusankar et al., reported an up to 23% cytochrome P450 inhibitory effect with significant inhibition on CYP3A4 and CYP2D6. [3] To use TP, a careful consideration of drug interaction must be taken into account. [4] Based on the disturbance of cytochrome activity, drug interaction with several drugs including tamsulosin (drug for benign prostatic hypertrophy), oxycodone (a kind of opioid analgesic drug) and tilidine (a kind of opioid analgesic drug) can be expected. Of interest, since TP is also described as having benefit for cancer treatment, [5] therefore interaction with those drugs that can be used in cancer patients may also occur.

 
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1.Gupta SK, Kalaiselvan V, Srivastava S, Agrawal SS, Saxena R. Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies. J Ayurveda Integr Med 2010;1:280-6.  Back to cited text no. 1
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2.Tandon S, Gupta K, Rao S, Malagi KJ. Effect of Triphala mouthwash on the caries status. Int J Ayurveda Res 2010;1:93-9.  Back to cited text no. 2
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3.Ponnusankar S, Pandit S, Babu R, Bandyopadhyay A, Mukherjee PK. Cytochrome P450 inhibitory potential of Triphala: A Rasayana from Ayurveda. J Ethnopharmacol 2011;133:120-5.   Back to cited text no. 3
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4.Wiwanitkit V. More concerns on triphala mouthwash. Int J Ayurveda Res 2010;1:196.  Back to cited text no. 4
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5.Baliga MS. Triphala, Ayurvedic formulation for treating and preventing cancer: A review. J Altern Complement Med 2010;16:1301-8.  Back to cited text no. 5
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